Laureates of the Japan Prize

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Jennifer A. Doudna, Ph.D.

2017 (33rd) Japan Prize Laureate

Field
Life Science
Achievement
Elucidation of the genome editing mechanism by the CRISPR-Cas
Commemorative Lecture
A CRISPR World: From Biology to Technology of Genome Editing
Nationality: United States of America
Date of Birth: February 19, 1964
Education:
1985 Pomana College, B.A. in Biochemistry
1989 Harvard Medical School, Ph.D. in Biological Chemistry and Molecular Pharmacology
Research and Career:
1989-91 Research Fellow, Massachusetts General Hospital;
Harvard Medical School
1991-94 Postdoctoral Scholar, University of Colorado
1994-02 Yale University, Assistant Professor, Associate Professor,
Professor, Henry Ford II Professor
1997- Investigator, Howard Hughes Medical Institute
2002- Professor, University of California, Berkeley
Affiliation:
University of California, Berkeley
Department of Chemistry and Chemical Engineering
708A Stanley Hall, Berkeley, CA 94720-3220
Publication, Thesis:
  1. Haurwitz RE, Wiedenheft B, Zhou K, Doudna JA. (2010) Sequence-and structure-specific RNA processing by a CRISPR endonuclease.
    Science 329(5997):1355-8.
  2. Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. (2012)
    A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity.
    Science 337(6096):816-21
  3. Sternberg SH, Redding S, Jinek M, Greene EC, Doudna JA. (2014)
    DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.
    Nature 507(7490):62-7 PMCID: PMC4106473
  4. Kranzusch PJ, Lee AS, Wilson SC, Solovykh MS, Vance RE, Berger JM, Doudna JA. (2014)
    Structure-guided reprogramming of human cGAS dinucleotide linkage specificity.
    Cell 158(5):1011-21 PMCID: PMC4157622
  5. O'Connell MR, Oakes BL, Sternberg SH, East-Seletsky A, Kaplan M, Doudna JA. (2014)
    Programmable RNA recognition and cleavage by CRISPR/Cas9.
    Nature 516(7530):263-6 PMCID: PMC4268322
Awards:
  • 1999 National Academy of Sciences Award for Initiatives in Research
  • 2000 Alan T. Waterman Award, National Science Foundation
  • 2014 Lurie Prize in Biomedical Sciences, Foundation for the NIH
  • 2015 Breakthrough Prize in Life Sciences*
  • 2015 Princess of Asturias Award of Technical and Scientific Research*
  • 2016 Canada Gairdner International Award**
  • 2016 Tang Prize (Biopharmaceutical Science), Taiwan**

* Jointly received with E. Charpentier
** Jointly received with E. Charpentier and F. Zhang

Recognition:
  • 2002 Member, National Academy of Sciences
  • 2003 Member, American Academy of Arts and Sciences
  • 2010 Member, Institute of Medicine of the National Academies

(As of January 2017)

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